The Spiders won their first CAA conference game in almost two years by winning at Villanova for the first time since 2000.
JMU remained undefeated in the CAA by beating last year conference champions Towson.
Virginia State and Virginia Union won their first CIAA conference games of the year. The Trojans beat Elizabeth City State while the Panthers drop 61 points on Lincoln.
John Marshall suffered their first loss of the season with a 28-6 defeat to Mills Godwin.