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Fatalities, injures reported in Tennessee highway wreck

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(CNN) — A wreck Wednesday involving a tractor-trailer, tour bus and passenger vehicle resulted in multiple fatalities and injuries, the Tennessee Highway Patrol said.

The wreck occurred about 40 miles east of Knoxville on Interstate 40 westbound near the 423 mile marker, said Tennessee Department of Safety spokeswoman Dalya Qualls.

The bus was traveling east on I-40 and crossed the median, struck the tractor-trailer and the passenger car, Qualls told CNN.

The tractor-trailer caught fire and the bus overturned, she said.

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